Conor McKerr became the youngest Derbyshire bowler to take ten wickets in a match, but he could not prevent defeat in the Specsavers County Championship fixture against Northamptonshire.
The 19-year-old fast bowler, who is on loan from Surrey, finished with match figures of 10-141 as Derbyshire took six wickets in the opening hour to bowl Northamptonshire out for 277.
Wickets continued to tumble, and despite resistance from Tom Taylor (69) and Daryn Smit (29 not out), Derbyshire were all out for 191, losing by 128 runs.
Derbyshire began the fightback in the fifth over of the morning when Nathan Buck was bowled by Taylor for eight. McKerr then struck twice in the following over, first Ben Duckett lbw for eight before Josh Cobb was bowled without scoring.
Tony Palladino had Chesney Hughes lbw for eight and the hosts were soon nine down as Jeevan Mendis had Ben Sanderson caught in the deep.
McKerr took the final wicket, Rory Kleinveldt bowled for nine, with the hosts all out for 277. The pace bowler completed his five-wicket haul and returned career-best figures of 5-54, to add to his 5-87 in the first innings.
Chasing 320 to win, Billy Godleman opened with Jeevan Mendis in the absence of Luis Reece.
Godleman was the first wicket to fall, caught at mid-wicket off Sanderson for two. The opening bowler then removed Mendis lbw for five and Shiv Thakor caught by Cobb for six as Derbyshire slipped to 21-3.
Wayne Madsen was out shortly after lunch, dragging onto his stumps off Sanderson for four. Gary Wilson was run out for seven before Alex Hughes, who provided resistance during his 23, was lbw to Buck.
Taylor and Smit added 106 for the seventh wicket as Taylor hit his second highest first-class score of 69, including 12 fours. He was caught behind by Duckett off Buck and Palladino soon followed, caught by Wakely in the slips off the same bowler.
Smit was unbeaten on 29 as McKerr was the last wicket to fall, bowled by Rob Keogh for 17, Derbyshire all out for 191.
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