Billy Godleman (102) scored a century for Derbyshire on Day One of the Specsavers County Championship game against Middlesex.
Fynn Hudson-Prentice struck 99, while Luis Reece (96) and Leus du Plooy (50 not out) also scored half-centuries as the hosts closed on 372-4.
The East Midlands Rivalry! Guarantee your tickets today for the big Vitality Blast clash against Notts Outlaws on Friday 26 July. Buy online or call 01332 388 101.