Luis Reece, Harry Came and Haider Ali all scored half-centuries, but Derbyshire were defeated by Glamorgan in the Metro Bank One Day Cup.
Colin Ingram scored an unbeaten 115 off 108 balls and Kiran Carlson 65 from 52 as Glamorgan chased down Derbyshire’s 298 for 8 with 17 balls to spare.
Billy Root helped seal victory with an unbeaten 34 from 31 balls in a stand of 82 from 76 balls with Ingram who ended the match with a six off Luis Reece.
The home side were on course for a more imposing total after Harry Came with 73 and Reece 69 shared an opening stand of 134.
But Haider Ali’s dismissal for 63 from 50 balls sparked a collapse that saw Derbyshire lose five wickets for 26 runs in six overs and the visitors were always favourites once Ingram and Carlson took control.
It had promised to be a better day for Derbyshire when Reece and Came began to accelerate with Came pulling a free hit from Ben Morris for the first six of the innings in the 11th over.
A scoop over the wicketkeeper took Reece to his 50 from 52 balls but after he was hit on his right elbow by a throw, he scored only four more runs before he came down the pitch and was stumped to give Ben Kellaway his first List A wicket.
Kellaway was involved again when his direct hit from backward point ran out Came and then struck Alex Horton a painful blow on the ankle which left the wicketkeeper requiring treatment before he could continue.
By then, Ali was starting to bruise the bowler’s figures, pulling and driving two big sixes on his way to a 42 ball fifty.
Kellaway was hoisted onto the pavilion roof but after cutting the off-spinner for his fifth four, Ali sliced a big drive and was caught at point.
From then on the innings went into decline with Matt Lamb missing an expansive drive and Tom Wood lbw trying to shovel Kiran Carlson through mid-wicket.
Brooke Guest was well caught on the run at mid-wicket and Anuj Dal was bowled attempting to scoop Andy Gorvin.
Derbyshire had fallen well short of what looked likely six overs earlier but some improvisation from Sam Conners and a six by Alex Thomson off the final ball of the innings took them to their highest Lisa A score against Glamorgan.
The visitors established a solid base but after Tom Bevan drove a Nick Potts no ball for four and pulled the free hit for six, both openers went in consecutive overs.
Bevan skied Dal to deep mid-wicket and Eddie Byrom was caught behind trying to steer Potts to third man.
But Ingram and Carlson kept Glamorgan ahead of the required rate and after a short rain break, Ingram carved Conners over cover for six to take his side to 142 for 2 at the halfway point.
Carlson pulled Wood for six to reach 50 from 40 balls but when he tried to sweep Thomson, he got a top edge and was caught at short fine leg.
But Ingram made sure there was no late drama as he and Root secured Glamorgan’s first victory in the competition to send Derbyshire sliding to a second defeat.
Derbyshire opener Harry Came said: “I think we were about 30 short ,especially being two down for nearly 200 we would have liked to have got at least 330 from there.
“Hopefully for Wednesday we will have learned our lessons and come back and put plenty of runs on the board.
“At 100 for 2 we were right in the game but they didn’t have to take too many risks and they had a few soft balls which got them away which was very frustrating for us and that’s something we are going to look to put right.”
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